Clear Signs

Clear view, clear benefit.

n this issue of the Journal, a clinical investigation by Ozaki et al focuses on the flushing solution used for image acquisition with frequency-domain optical coherence tomography (FD-OCT).1 The authors present the cross-sectional area measurement as a quantitative evaluation using low-molecular dextran L (LMD-L) approximate to that of contrast media, and the non-inferiority of LMD-L to contras...

Golf Signs GOLF SIGNS

PHYSICAL SIGNS False localising signs

Neurological signs have been described as “false localising” if they reflect dysfunction distant or remote from the expected anatomical locus of pathology, hence challenging the traditional clinicoanatomical correlation paradigm on which neurological examination is based. False localising signs occur in two major contexts: as a consequence of raised intracranial pressure, and with spinal cord l...

Crystal clear

The British synchrotron radiation source (SRS) at Daresbury, Cheshire was a pioneering achievement when it started work in 1981. It was the first accelerator ring to be built for the main purpose of harvesting the highly focused synchrotron radiation from electrons travelling round in circles at extremely high speeds. It became an invaluable facility for high-resolution X-ray crystallography an...

Crystal clear

There is growing scientific evidence of climate change at the Earth’s poles but also increasing worries that most people, living in more temperate latitudes, are failing to grasp the significance of these events. And it is not just scientists that are worried by this perception gap: many artists are also concerned about the apparent failure to grab public attention over these issues. A new exhi...